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To learn more about the surgical weight loss program call 270-688-1500 or email us.

Janet Carlo, RN, BSN, CBN
Janet Carlo, RN, BSN, CBN - Director, Bariatric Services 

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Obesity - Causes and Conditions

What does "Obesity" mean?

Obesity is a disease that occurs when fat has accumulated in an individual to the point that their health is impaired. It is a complex disease that is both caused and made worse by a number of factors. Obesity is very commonly a lifelong disease that gets worse over time and has increasingly negative effects. It is ultimately deadly, either on its own or by contributing to other serious health problems.

Amber Thompson

Amber's Surgical Weight Loss Story

Weight loss surgery with Dr. Alapati from Owensboro Health changed her life.

Read and watch Amber's story.

Conditions associated with obesity

Health problems caused or worsened by obesity (called comorbidities) include:

  • Stroke
  • Circulatory problems
    • Hypertension
    • Circulatory inflammation (phlebitis and venous stasis)
  • Lung and breathing problems
    • Obstructive sleep apnea
    • Diminished breathing capacity and ability to work without becoming short of breath
  • Metabolic diseases
    • Diabetes
    • Metabolic syndrome
    • Dyslipidemia and high cholesterol
  • Gastrointestinal and liver problems
    • Fatty liver disease (steatosis)
    • Fatty liver inflammation (steatohepatitis)
    • Liver damage and scarring (cirrhosis)
    • Gastro-esophageal Reflux Disease (GERD)
    • Pancreas inflammation (pancreatitis)
    • Gallbladder disease
  • Osteoarthritis
  • Hypertension
  • Gout
  • Cancer
    • Breast, uterus, cervical, colorectal, esophagus, pancreas, kidney, prostate
  • Reproductive issues (female)
    • Abnormal menstrual cycle
    • Infertility
    • Polycystic ovarian syndrome
    • Stress incontinence
  • Depression


Factors that cause or influence obesity can be:

  • Genetic
  • Environmental
  • Lifestyle- and behavior-related
  • Psychological
  • Physiological
  • Metabolic

The human body has what is called the metabolic “set point.” This set point is different for everyone, and it’s how the body decides to regulate its metabolism and how it uses food for energy. When you try to lose weight, the body sees your efforts as a threat and acts to defend itself from starvation. This lowers your metabolism and makes you hungrier.

The set point is very difficult to change and it can remain high even months after a person loses weight. What often happens then is a sort of “rubber band” effect, where they gain back the weight they lost and then gain even more. This causes a cycle of weight loss and gain.

That cycle usually works like so:

  1. Diet and exercise to reduce weight
  2. Metabolic and hormonal changes slow metabolism and increase hunger (both of which make it more difficult to lose weight); these changes can persist long after weight has been lost
  3. Weight re-gain (often to an even higher weight than before)
  4. Cycle begins again

Obesity Is Not An Isolated Problem

Obesity is a problem nationally, and especially in Kentucky. Nationwide, 70% of adults have a Body Mass Index of 25 or above, making them overweight or obese. Additionally, 6.3% of that number are extremely obese, meaning they have a BMI of 40 or greater. Among children, 17% are obese. A 2005 paper in the Journal of the American Medical Association estimated that 112,000 obesity-related deaths occur every year.

Obesity is a costly disease. In 2011, it was estimated that obesity and related diseases or problems cost approximately $127 billion annually in the United States.

Visit the CDC website and look at obesity prevalence maps to see the rise in obesity rates throughout the years.